The Nanosurf Flex-ANA system is an automated solution for AFM-based nanomechanical analysis. It is designed to investigate the nanomechanical properties of materials such as cells, tissues, scaffolds, hydrogels, and polymers on multiple or large samples via force spectroscopy and force mapping in an intuitive and automated fashion.
Key features and benefits
The combination of a straight-forward experimental and post-processing workflow, selected hardware elements, and thought-through, well-designed control algorithms are hallmarks of the Flex-ANA system. Measurement locations on large or multiple samples are defined using an overview image with a large field-of-view that covers the entire accessible 32 mm × 32 mm sample area. Height differences of up to 5 mm can be overcome automatically by the system!
During an experiment, smart algorithms coordinate the movement of the scan head and the motorized XYZ translation stage (32 mm × 32 mm × 5 mm range), which can optionally be equipped with an additional 100-µm Z piezo for an extended spectroscopy range. To cope with large sample height variations, proprietary algorithms permanently monitor and optimize the sample position with respect to the probing cantilever and drive all Z elements accordingly. Thus, soft and sticky samples, as well as samples with macroscopic and microscopic roughness in the range of several millimeters and micrometers, respectively, can be easily addressed.
Besides conducting automated nanomechanical measurements, the Flex-ANA system offers advanced data post-processing and analysis capabilities: